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Epitopes

Short descriptions of antigenic markers

Staining for these markers have either been assessed or an assessment is planned in the near future.

Click on a marker to see a characterization of the proteins, their occurrence in neoplastic cells, the diagnostic application of the markers, aspects of visualization including controls, and results of NordiQC schemes and protocols.

 

A

F

alpha-methylacyl-CoA racemase (AMACR)

Factor VIII related antigen (FVIII)

alpha-smooth muscle actin (ASMA)

G

Anaplastic lymphoma kinase (ALK)

Gross cystic fluid protein-15

B

Glial fibrillary acidic protein (GFAP)

B-cell specific activator protein (BSAP, Pax5)

H

bcl-2 protein

Hepatocyte antigen (Hepa)

bcl-6 protein

HER-2

C

Human chorionic gonadotropin (HCG)

Calretinin (CR)

I

Cancer antigen 125 (CA125)

Immunoglobulins (Ig)

Carcinoembryonic antigen (CEA)

K

CD3

Ki-67

CD4

M

CD5

Mammaglobin

CD8

Melan-A (MLA)

CD10

Melanosoma specific antigen (MSA, HMB-45)

CD14

Mismatch repair (MMR) proteins

CD15

Multiple myeloma oncogene 1 (MUM1)

CD19

Myosin (SMH)

CD20

N

CD23

Neurofilament protein (NFP)

CD30

O

CD31

OCT3/4

CD34 

P

CD45

p16ink4a

CD56

p53

CD68

p63

CD79a

Paired Paired box gene protein 2 (PAX2)

CD99

Paired Paired box gene protein 8 (PAX8)

CD117

Placental Alkaline Phosphatase (PLAP)

CD138

Podoplanin (Podop)

CD163

Progesterone receptor (PR)

Cdx-2

Prostate-specific antigen (PSA)

Chromogranin (CGA)

Prostatic acid phosphatas (PAP)

Cyclin D1 (CyD1)

Prostein

Cytokeratins (CKs)

S

D

S-100 protein beta (S100)

Desmin Synaptophysin (SYP)
E T
E-cadherin

Terminal deoxynucleotidyl transferase (TdT)

Epithelial cell-cell adhesion mol. (Ep-CAM)

Thyroid transcription factor-1 (TTF1)
Epithelial membrane antigen (EMA) V
Estrogen receptor (ER)

Vimentin (VIM)

  W

 

Wilm's tumour-1 protein (WT1)
MV/AS

Last update 22-08-2012