Recommended control tissue

Multitissue controlblock

On the basis of the observations generated during the NordiQC assessments concerning identification of recommended control tissue, NordiQC and Aalborg Sygehus DK, Department of Pathology have established a database with suggestions how to design multitissue controlblocks and interpret the immunohistochemical reactions in these.

The database is based on 4 controlblocks consisting of preferable normal tissue. For each marker the reaction pattern is described and if possible quality indicators (text marked with red) either identified by NordiQC or personal experiences serve as quality indicator for the diagnostic use of the marker.

Multitissue controlblock 1
Appendix, tonsil, pancreas and liver

Multitissue controlblock 2
Brain, striated muscle, skin and melanoma

Multitissue controlblock 3
Lung, thyroid, prostate and placenta

Multitissue controlblock 4
Thymus, bone marrow, Hodgkin lymphoma and tonsil

The design of the multitissue controlblocks is only a guideline and can be modified to the individual laboratory.