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2007 modules

General module

Events

Run 19

Run 20

Run 21

Epitopes to be detected1)
 (click for updated monographs)

CD23, CR, CyD1, Ki67, Podop, TTF1, CK-LMW, CK-Pan, MLA, MSA, p53, S100 ASMA, CD20, CD79a, CD117, CD138, DES

Abbreviations: ASMA: alpha-smooth muscle antigen; CK-LMW: Cytokeratin, low molecular weight (the Ab should detect at least one primary/constitutive CK of simple epithelia, i.e., CK8 or CK18); CK-Pan: Pan- or broad spectrum cytokeratin (the Ab should detect at least one primary/constitutive CK of simple epithelia, i.e., CK8 or CK18, and one primary/constitutive CK of squamous epithelia, i.e., CK5 or CK14); CR: Calretinin; CyD1: cyclin D1; DES: desmin; MLA: Melan A; MSA: melanosoma specific antigen (HMB-45); Podop: podoplanin = D2-40; TTF1: thyroid transcription factor-1.


Breast module

Events

Run B3

Run B4

Epitopes to be detected1)

ER, HER-21) HER-21), PR
1) If a laboratory is unable to stain for HER-2, it can be replaced by PR in Run B3 and ER in Run B4. Use the field "Other epitope" in the protocol form.

Abbreviations: ER: Estrogen receptor, PR Progesterone receptor

2006 modules

General module

Events

Run 16

Run 17

Run 18

Epitopes to be detected1)
(click for updated monographs)

AMACR, CD10, CK-LMW, CK-HMW, MLA, p63

ALK, bcl-6, CD5, CR,

CyD1, Ep-CAM

CGA, IgK, IgM, NFP, Syp, TdT

Abbreviations: ALK: Anaplastic lymphoma kinase, AMACR: alpha-methylacyl-CoA racemase, (P504S protein), CGA: chromogranin A, CK-HMW: Cytokeratin, high molecular weight (the Ab should detect at least one primary/constitutive CK of complex/stratified epithelia, ie., CK5 or CK14), CK-LMW: Cytokeratin, low molecular weight (the Ab should detect at least one primary/constitutive CK of simple epithelia, i.e., CK8 or CK18), CR: Calretinin, CyD1: Cyclin D1, Ep-CAM: Epithelial cellular adhesion molecule (Abs., e.g., Ber-EP4 or MOC-31); IgK: Immunoglobulin Kappa; IgM: Immunoglobulin M; NFP: Neurofilament protein, Syp: Synaptophysin, TdT: Terminal deoxynucleotidyl transferase.


Breast module
     

Events

Run B1

Run B2

Epitopes to be detected1)

HER-21), ER HER-21), PgR
1) If a laboratory is unable to stain for HER-2, it can be replaced by PgR in Run B1 and ER in Run B2. Use the field "Other epitope" in the protocol form.

Abbreviations: ER: Estrogen receptor, PgR Progesterone receptor

MV/AS  

Last update 01-11-2007