|
General module |
|
Events |
Run 19 |
Run 20 |
Run 21 |
|
Epitopes
to be detected1)
(click for updated monographs)
|
CD23,
CR,
CyD1,
Ki67,
Podop,
TTF1, |
CK-LMW,
CK-Pan,
MLA,
MSA,
p53, S100 |
ASMA,
CD20,
CD79a,
CD117,
CD138,
DES |
|
Abbreviations: ASMA: alpha-smooth muscle
antigen; CK-LMW:
Cytokeratin, low molecular weight (the Ab should detect at least one primary/constitutive CK of simple epithelia, i.e., CK8 or CK18);
CK-Pan: Pan- or broad spectrum cytokeratin (the Ab should detect at
least one primary/constitutive CK of simple epithelia, i.e., CK8 or
CK18, and one primary/constitutive CK of squamous epithelia,
i.e., CK5 or CK14); CR: Calretinin;
CyD1: cyclin D1; DES: desmin; MLA: Melan A; MSA: melanosoma specific
antigen (HMB-45); Podop: podoplanin = D2-40; TTF1: thyroid
transcription factor-1. |
Breast module |
|
Events |
Run B3 |
Run B4 |
|
Epitopes
to be detected1)
|
ER,
HER-21) |
HER-21),
PR |
|
1) If a laboratory is unable to stain for HER-2, it can be
replaced by PR in Run B3 and ER in Run B4. Use the field "Other
epitope" in the protocol form. |
|
Abbreviations: ER: Estrogen receptor, PR
Progesterone receptor |
|
|
General module |
|
Events |
Run 16 |
Run 17 |
Run 18 |
|
Epitopes to be detected1)
(click for updated monographs)
|
AMACR,
CD10,
CK-LMW,
CK-HMW,
MLA,
p63 |
ALK,
bcl-6,
CD5,
CR,
CyD1,
Ep-CAM |
CGA,
IgK,
IgM,
NFP,
Syp,
TdT |
|
Abbreviations: ALK: Anaplastic lymphoma kinase,
AMACR: alpha-methylacyl-CoA racemase, (P504S protein), CGA:
chromogranin A, CK-HMW: Cytokeratin, high molecular weight (the Ab
should detect at least one primary/constitutive CK of
complex/stratified epithelia, ie., CK5 or CK14), CK-LMW: Cytokeratin,
low molecular weight (the Ab should detect at least one
primary/constitutive CK of simple epithelia, i.e., CK8 or CK18), CR:
Calretinin, CyD1: Cyclin D1, Ep-CAM: Epithelial cellular adhesion
molecule (Abs., e.g., Ber-EP4 or MOC-31); IgK: Immunoglobulin Kappa;
IgM: Immunoglobulin M; NFP: Neurofilament protein, Syp: Synaptophysin,
TdT: Terminal deoxynucleotidyl transferase. |
Breast module |
|
|
|
|
Events |
Run B1 |
Run B2 |
|
Epitopes to be detected1)
|
HER-21),
ER |
HER-21),
PgR |
|
1) If a laboratory is unable to stain for HER-2, it can be
replaced by PgR in Run B1 and ER in Run B2. Use the field "Other
epitope" in the protocol form. |
|
Abbreviations: ER: Estrogen receptor, PgR
Progesterone receptor |
|
