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Fig. 1A. Normal prostate stained for
p63. The nuclei of basal cells are stained. However, in some glands
only few basal cells are discerned (upper part of picture). |
Fig
1B.
Normal prostate stained for p63 and AMACR ("PIN cocktail"). The
nuclei of basal cells are p63 positive. The cytoplasm of the
secretory cells are weakly AMACR positive. |
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Fig. 1C. Prostate adenocarcinoma
stained for p63 and AMACR ("PIN cocktail"). The cytoplasm of the
tumour cells are heterogeneously AMACR positive. No p63 positive
nuclei are revealed. |
Fig
1D.
Prostate adenocarcinoma stained for p63 and AMACR ("PIN cocktail").
The cytoplasm of the tumour cells are AMACR positive. Normal glands
with p63 positive basal cell nuclei are seen (upper pert of the
picture). |
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Fig. 1E. Prostate adenocarcinoma in
situ stained for cytokeratin 5, p63 and AMACR. The cytoplasm of the
neoplastic cells are AMACR positive. The basal cells are p63
positive in the nuclei and cytokeratin 5 positive in the cytoplasm.
The staining for two proteins in the basal cells enhances the
cellular outlining without obscuring the pattern. |
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