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Intermediate filaments |
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Together with microtubules and microfilaments, intermediate filaments (IFs) build up the cytoskeleton of almost all eukaryotic cells. Cytoplasmic IFs are polypeptide filaments with a diameter of about 10 nm, forming a dense network radiating from the nucleus and extending to the plasma membrane. On the basis of their composition of specific polypeptide subunits, IFs are divided into five classes comprising ten groups:
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