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NordiQC is an independent scientific organization, promoting the quality of immunohistochemistry by arranging schemes for pathology laboratories, assessing tissue stains, giving recommendations for improvement and providing good protocols.

Last update: 12-01-2012

The results of Run 33, B12 and G2 are available as of 7th December. See Newsletter.

Run 34 (General module) in scheme 2012 is closed for protocol submission. The deadline was 9th January. Slides were circulated about 14th January, and deadline for return of slides is 6th  Feb.
For changes in previously submitted protocols: Go to Participation.

Run 35 (General module) and B13 (Breast cancer IHC module) opens by 1st April. HER2-ISH is no longer included in the latter and is in B13 replaced by Ki67.

Run H1 in the new HER-2 ISH module also opens by 1st April.
It comprises two annual runs with in situ hybridization tests for HER-2. This module includes both BRISH and FISH.

Figure: CDX2 staining: A) Normal pancreas giving a weak-moderate, distinct nuclear reaction in scattered ducts. B) Typical case of a false negative reaction in pancreas because of less successful antibody or insufficient protocol. C) Colon adenocarcinoma: With the same protocol as used in A, a strong nuclear staining is seen. D) With the same tumour as shown in C and the same protocol as used in B, only an ambiguous nuclear reaction is obtained. Pancreas is a low expressor for CDX2 and should be included as control tissue. Take care that the pancreas is fixed without delay, otherwise it may become false negative and thus, useless for control.

  
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